Goat Secondary Antibodies
Cayman Chemical 2′-O-Methylcytidine, Purity: ≥98%, CAS: 2140-72-9, 5 g
An inhibitor of HCV NS5B (IC50 = 3.8 µM); inhibits HCV replication in a replicon assay (IC50 = 21.2 µM)
Cayman Chemical Tetrahydroxyquinone, Purity: ≥98%, CAS: 319-89-1, 5 g
A redox-active hydroxyquinone; inhibits HIV-1 proteinase (IC50 = 575 µM) and is active against T. brucei brucei (MIC100 = 100 µg/ml); induces ROS formation and apoptosis in HL-60 leukemia cells at 100 µM
Cayman Chemical (±)-Hydroxycitric Acid (technical grade), CAS: 6205-14-7, 1 g
A hydroxy derivative of citric acid
Cayman Chemical 1-(4-Chlorobenzhydryl)piperazine, Purity: ≥98%, CAS: 303-26-4, 10 g
An inactive metabolite of meclizine and chlorcyclizine; has been found as an impurity in commercial preparations of hydroxyzine and cetirizine; has been used in the synthesis of Nav1.7 inhibitors, anticancer agents, and antihistamines
Cayman Chemical SauvagIntrIfluoroACTAte500ug
A neuropeptide hormone; reduces systemic blood pressure in normotensive rats at 0.5 UG/kg, s.c.; inhibits anterior pituitary release of prolactin, TSH, and growth hormone in rats; increases plasma ACTH levels in rats
Cayman Chemical Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt), Purity: ≥98%, 10 mg
A synthetic peptide fragment of galanin and an agonist of the GAL2 receptor (EC50 = 9.32 nM in a fluorescence imaging plate reader assay); selectively binds to the GAL2 receptor (IC50 = 1.76 nM for the rat receptor) over the GAL1 receptor (IC50 = 879 nM for the human receptor) but does also bind to the GAL3 receptor (Ki = 271 nM for the rat receptor); decreases immobility in the forced swim test in rats at 1 nmol/animal, i.c.v.; reduces the hind paw mechanical pain threshold and increases the hind paw cold sensitivity threshold in rats
Cayman Chemical Tylvalosin (tartrate), Purity: ≥80%, CAS: 63428-13-7, 1 g
A macrolide antibiotic; active against S. aureus, E. coli, and P. multocida (MICs = 2, 128, and 128 µg/ml, respectively); reduces LPS-induced production of pro-inflammatory cytokines, prostaglandin E2 (PGE2; Item No. 14010), and nitric oxide in RAW 264.7 cells at 5 and 10 µg/ml; reduces the severity of lung lesions in pigs infected with M. hyopneumoniae and P. multocida at 10 mg/kg per day in the drinking water
Cayman Chemical Thioacetazone, Purity: ≥98%, CAS: 104-06-3, 1 g
An antitubercular agent; active against M. tuberculosis H37Rv, M. kansasii Bostrom, and M. avium serotype 2 (MICs = 0.3, 0.6, and 20 µg/ml, respectively)
Cayman Chemical Cholenic Acid, Purity: ≥98%, CAS: 5255-17-4, 250 mg
A bile acid; formed by 7α-hydroxylation of 27-hydroxycholesterol; precursor in the biosynthesis of chenodeoxycholic acid; levels are increased in patients with neonatal liver disease harboring mutations in CYP7A1, as well as in patients with intrahepatic and extrahepatic cholestasis
Cayman Chemical 5'-Deoxyadenosine, Purity: ≥95%, CAS: 4754-39-6, 250 mg
An adenosine analog; an intermediate in the degradation of S-adenosyl-L-methionine; has been used in the study of enzyme kinetics, including those of phosphomethylpyrimidine synthase, glutamate mutase, and 5’-methylthioadenosine phosphorylase
Cayman Chemical 2-Chloroadenine, Purity: ≥98%, CAS: 1839-18-5, 250 mg
A heterocyclic building block; has been used in the synthesis of adenosine antimetabolites with antineoplastic activity; the major catabolite of 2-chloro-2’-deoxyadenosine
Cayman Chemical Otilonium (bromide), Purity: ≥98%, CAS: 26095-59-0, 5 g
An L- and T-type calcium channel inhibitor (IC50s = 2.3, 0.8, 1.1, and 0.4 µM for Cav1.2, Cav3.1, Cav3.2, and Cav3.3, respectively) and mAChR antagonist (IC50s = 0.054, 0.4, 0.222, and 0.156 µM for M1, M2, M4, and M5 muscarinic receptors, respectively); inhibits the PAF receptor (IC50 = 0.0552 µM); inhibits the inward calcium current in isolated rat colonic smooth muscle cells (EC50 = 885 nM), an effect that can be blocked by an L-type calcium channel inhibitor; inhibits mAChR agonist-induced contractions in isolated circular muscle of the guinea pig proximal colon (IC50 = 3.7 µM); decreases fecal excretion and wet dog shakes and increases the tail withdrawal latency in the tail-flick test in a rat model of morphine- and naloxone-induced opioid withdrawal syndrome at 4 mg/kg
Cayman Chemical α-Arbutin, Purity: ≥98%, CAS: 84380-01-8, 50 g
A glycosylated hydroquinone with diverse biological activities; inhibits tyrosinase in a cell-free assay (IC50 = 0.48 mM for the mouse enzyme); inhibits production of melanin in HMV-II cells at 0.5 mM; prevents rotenone-induced increases in ROS in SH-SY5Y cells at 100 µM; decreases locomotor deficits in a parkin-null transgenic Drosophila model of Parkinson's disease; reduces postprandial plasma glucose levels in mice at 30 mM; has been used in the synthesis of α-glucosidase inhibitors
Cayman Chemical Prulifloxacin, Purity: ≥98%, CAS: 123447-62-1, 500 mg
A prodrug from of ulifloxacin; increases survival in various mouse models of systemic bacterial infection (ED50s = 0.35-23 mg/kg); increases survival in a mouse model of K. pneumoniae-induced respiratory tract infection (ED50 = 0.981 mg/kg)
Immunoreagents Inc GOAT A-HUMAN IGA AP 1 MG
Secondary Antibody; Goat anti-human IgA Alpha Chain, Affinity Pure, Host: Goat, Format: Liq, Label: None , Applications: WB, ELISA, IHC/ICC, IF, IP, FC